Polycystic kidney disease is a kidney disorder passed down through families in which multiple cysts form on the kidneys, causing them to become enlarged.And it is a type of kidney disease. It also known as polycystic kidney syndrome, and It is a cystic genetic disorder of the kidneys.[1] There are two types of PKD: Autosomal Dominant Polycystic Kidney Disease (ADPKD) and the less-common Autosomal Recessive Polycystic Kidney Disease (ARPKD).
And how to Prognosis of Polycystic Kidney Disease
The individual differences is obvious for patients with Polycystic Kidney Disease. The prognosis is closely related to the course of disease and whether there is serious complications. The prognosis is worse for patients with more complications and progressing Uremia. Some patients have Renal Insufficiency, but there is no complication and the progressing of the disease is slow, the prognosis will be better. Therefore, the treatment for complications becomes the key point that influence the prognosis.
The controllable factors that influence the prognosis of Polycystic Kidney Disease are hypertension, times of pregnancy, secondary UTI and the frequency of UTI. If there is no dialysis or kidney transplant, patients with PKD can only live for 10 years after the symptoms appear. The serum creatinine will double every 3 years. For patients on dialysis and kidney transplant, the prognosis is similar to patients with other kind of kidney disease.
In order to improve the prognosis and prolong the life of the patients, the choice of treatment is very important.
In Shijiazhuang Kidney Disease Hospital, we mainly use combined therapy of both Chinese medicine and western medicine to treat PKD. That is Micro-Chinese Medicine Osmotherapy. It acts directly on the progressing of renal fibrosis and stop the development of the disease. After entering the human body, the active material of micro-Chinese medicine can expand the blood vessels, anti inflammation, anti coagulation and degrade the extra cellular matrix so as to improve the blood supply in all the organs, eliminate inflammatory reaction and restrain formation. It will block the renal fibrosis dimensionally, promote reversal of phenotype of kidney intrinsic cells and provide necessary nutrition for the repair of intrinsic cells.
There are some other points to pay attention to for better prognosis of Polycystic Kidney Disease.
1. For patients with hypertension or edema, give low salt or no salt diet.
2. The protein intake should be provided according to ordinary needs, that is 0.8~1.0g/kg every day for adults. Choose high quality protein such as eggs, milk and meat so as to avoid edema and anemia.
3. Take more food rich in vitamin A, B2 and C.
4. Water intake needs no limitation. Orange juice, water melon juice and vegetable juice can be taken for dieresis and removing edema.
Monday, 10 October 2011
Why People Got IgA Nephropathy and the Treatment
Why People Got IgA Nephropathy and the Treatment
IgA Nephropathy is a type of kidney disease. Now More and more people have get it.IgA nephropathy also known as berger's disease, a look at what it is, causes, incidence and risk factors. And it is a kidney disorder that occurs when IgA-a protein that helps the body fight infections-settles in the kidneys.
IgA Nephropathy is a kind of immune disease with mucosal damage. The reason why people got the disease is that there was a time when you have loss of immunity and the germs and viruses would invade the body leading to infection in upper tract or gastrointestinal tract. This will make the IgA of abnormal structure have antigenicity and stimulate the body to produce corresponding antibodies thus forming complex of antigen and antibodies. These complex are highly compatible to the binding protein and acceptors of glomerular mesangial cells and the combination of the two will induce the proliferation, multiplication and activation of the mesangial cells and secrete inflammatory factors and activated compliments, which will lead the renal ischemia and anoxia thus causing inflammatory damage to the glomerular mesangial cells.
It is not a fear of getting IgA Nephropathy. As long as we find corresponding treatment methods can we get rid of the disease. Line of Treatment for IgA Nephropathy
Using adrenocortical hormone(prednisone) on alternate days is helpful for patients with urine protein 1g/d. Prednisone can also reduce proteinuria for patients with minimal change disease of IgA deposition. Combined use of cyclophosphamide, persantin and warfarin can reduce the urine protein, but it has no effect on Glomerular Filtration Rate(GFR).
The immunosuppressive agents in western medicine have good effect in anti inflammation and restraining abnormal immune reaction. However, the pathological process of the kidneys is complex. Inflammation is only one circle of it. Only anti inflammation cannot solve the problem completely. What’s more, restraining the immune reaction can only stop the production of more IgA or other deposition, but has no effect on the deposited immune complex. Long time use of immunosuppressive agents has many serious side effects.
But what are Micro-chinese Medicine? Treatment for IgA Nephropathy With Blood Urine
The expert group of Shijiazhuang Kidney Disease Hospital has put forward ‘Each disease has its medicine and each medicine has its effect’ in the symposium of Chinese medical treatment of Nephropathy and Uraemia which was organized by Chinese Medical Society. And has put forward the authority idea and method of treating kidney disease-- the Micro-Chinese Medicine Osmotherapy.
Its four remarkable characteristics of new treatment method, quick effect, lasting efficacy as well as low cost created innumerable impressive medical miracles which raised unprecedented sensation in the domestic medical field and caused high attention of the colleagues at home and abroad as well as the innumerable patients.
The Micro-Chinese Medicine Osmotherapy has remarkable characteristics which are as the followings:
1.The efficacy of the medicine is enhanced.
2.Having high pertinence of treatment.
3.The biological active of the medicine is strengthened.
4. The repair of the kidney is strengthened.
Shijiazhuang Kidney Disease Hospital use different methods to treat IgA Nephropathy. The traditional treatment is only aimed at removing the hematuria, but our treatment is aimed at the root cause of hematuria. That is focusing on the repair of glomerular basement membrane. It is combined therapy of both Chinese medicine and western medicine with Chinese medicine as the core. We use Chinese medicine to expand the blood vessels, anti inflammation, anti coagulation and degrade harmful materials. The treatment of Chinese medicine adopts new combination to improve the effect of Chinese medicine and western medicine and developed hospital preparations. Among which the most advanced treatment is Micro-Chinese Medicine Osmotherapy for blocking renal fibrosis.
IgA Nephropathy is a type of kidney disease. Now More and more people have get it.IgA nephropathy also known as berger's disease, a look at what it is, causes, incidence and risk factors. And it is a kidney disorder that occurs when IgA-a protein that helps the body fight infections-settles in the kidneys.
IgA Nephropathy is a kind of immune disease with mucosal damage. The reason why people got the disease is that there was a time when you have loss of immunity and the germs and viruses would invade the body leading to infection in upper tract or gastrointestinal tract. This will make the IgA of abnormal structure have antigenicity and stimulate the body to produce corresponding antibodies thus forming complex of antigen and antibodies. These complex are highly compatible to the binding protein and acceptors of glomerular mesangial cells and the combination of the two will induce the proliferation, multiplication and activation of the mesangial cells and secrete inflammatory factors and activated compliments, which will lead the renal ischemia and anoxia thus causing inflammatory damage to the glomerular mesangial cells.
It is not a fear of getting IgA Nephropathy. As long as we find corresponding treatment methods can we get rid of the disease. Line of Treatment for IgA Nephropathy
Using adrenocortical hormone(prednisone) on alternate days is helpful for patients with urine protein 1g/d. Prednisone can also reduce proteinuria for patients with minimal change disease of IgA deposition. Combined use of cyclophosphamide, persantin and warfarin can reduce the urine protein, but it has no effect on Glomerular Filtration Rate(GFR).
The immunosuppressive agents in western medicine have good effect in anti inflammation and restraining abnormal immune reaction. However, the pathological process of the kidneys is complex. Inflammation is only one circle of it. Only anti inflammation cannot solve the problem completely. What’s more, restraining the immune reaction can only stop the production of more IgA or other deposition, but has no effect on the deposited immune complex. Long time use of immunosuppressive agents has many serious side effects.
But what are Micro-chinese Medicine? Treatment for IgA Nephropathy With Blood Urine
The expert group of Shijiazhuang Kidney Disease Hospital has put forward ‘Each disease has its medicine and each medicine has its effect’ in the symposium of Chinese medical treatment of Nephropathy and Uraemia which was organized by Chinese Medical Society. And has put forward the authority idea and method of treating kidney disease-- the Micro-Chinese Medicine Osmotherapy.
Its four remarkable characteristics of new treatment method, quick effect, lasting efficacy as well as low cost created innumerable impressive medical miracles which raised unprecedented sensation in the domestic medical field and caused high attention of the colleagues at home and abroad as well as the innumerable patients.
The Micro-Chinese Medicine Osmotherapy has remarkable characteristics which are as the followings:
1.The efficacy of the medicine is enhanced.
2.Having high pertinence of treatment.
3.The biological active of the medicine is strengthened.
4. The repair of the kidney is strengthened.
Shijiazhuang Kidney Disease Hospital use different methods to treat IgA Nephropathy. The traditional treatment is only aimed at removing the hematuria, but our treatment is aimed at the root cause of hematuria. That is focusing on the repair of glomerular basement membrane. It is combined therapy of both Chinese medicine and western medicine with Chinese medicine as the core. We use Chinese medicine to expand the blood vessels, anti inflammation, anti coagulation and degrade harmful materials. The treatment of Chinese medicine adopts new combination to improve the effect of Chinese medicine and western medicine and developed hospital preparations. Among which the most advanced treatment is Micro-Chinese Medicine Osmotherapy for blocking renal fibrosis.
A Brief Introduction of Purpura Nephritis
Purpura Nephritis is a common complication of purpura. Survey shows that about one third of patients with purpura develop Purpura Nephritis. In most cases, it occurs 4 weeks after occurrence of skin purpura. In order to help patients get to know this disease well, a brief introduction of Purpura Nephritis is presented here.
Signs and symptoms of Purpura Nephritis
◇ Hematuria, especially gross hematuria has a high incidence.
◇ Proteinuria refers to the condition in which people have protein in urine. The amount of protein in urine is various. Some patients with Purpura Nephritis have little, while others have much, even to the degree of Nephrotic Syndrome (over 3.5 grams per day).
◇ Swelling occurs due to leakage of protein and retention of water.
◇ Hypertension is caused by kidney problem and in turn it can further damage the kidneys, aggravating Purpura Nephritis.
◇ Impaired kidney function occurs if Purpura Nephritis is not treated properly and timely. When it happens, Purpura Nephritis is not easy to treat and have high risk of developing into renal failure.
Treatment of Purpura Nephritis
◇ Look for and remove allergen of purpura
This step is of great importance for treating Purpura Nephritis and preventing its relapse in the future.
◇ Steroids
Steroids have a good effect in relieving joint pain, gastrointestinal tract problem caused by purpura, but they have little effect in treating Purpura Nephritis. Even so, when patients have much protein in urine, steroids still are used.
◇ Chinese Herb Medicine
Chinese herb medicine, or rather Micro-Chinese Medicine Osmotherapy has good curative effect in treating Purpura Nephritis. The pathological change of Purpura Nephritis is deposition of IgA and immune complex in mesangial area, resulting in ischemia and anoxia of kidneys. Chinese herb medicine treats Purpura Nephritis by clearing up such deposition and improving blood circulation in kidneys. In this case, it treats this disease from root cause and therefore achieves good effects.
Prognosis of Purpura Nephritis
Prognosis of Purpura Nephritis is associated with many factors, including patient’s age, pathological type, severity and break out of skin purpura.
Usually, Purpura Nephritis in children has good prognosis; People with following pathological types have bad prognosis: sclerosis of glomerulus, fibrosis of renal interstitials and atrophy of renal tubules; prognosis is bad when a patient has frequent break out of skin purpura.
Signs and symptoms of Purpura Nephritis
◇ Hematuria, especially gross hematuria has a high incidence.
◇ Proteinuria refers to the condition in which people have protein in urine. The amount of protein in urine is various. Some patients with Purpura Nephritis have little, while others have much, even to the degree of Nephrotic Syndrome (over 3.5 grams per day).
◇ Swelling occurs due to leakage of protein and retention of water.
◇ Hypertension is caused by kidney problem and in turn it can further damage the kidneys, aggravating Purpura Nephritis.
◇ Impaired kidney function occurs if Purpura Nephritis is not treated properly and timely. When it happens, Purpura Nephritis is not easy to treat and have high risk of developing into renal failure.
Treatment of Purpura Nephritis
◇ Look for and remove allergen of purpura
This step is of great importance for treating Purpura Nephritis and preventing its relapse in the future.
◇ Steroids
Steroids have a good effect in relieving joint pain, gastrointestinal tract problem caused by purpura, but they have little effect in treating Purpura Nephritis. Even so, when patients have much protein in urine, steroids still are used.
◇ Chinese Herb Medicine
Chinese herb medicine, or rather Micro-Chinese Medicine Osmotherapy has good curative effect in treating Purpura Nephritis. The pathological change of Purpura Nephritis is deposition of IgA and immune complex in mesangial area, resulting in ischemia and anoxia of kidneys. Chinese herb medicine treats Purpura Nephritis by clearing up such deposition and improving blood circulation in kidneys. In this case, it treats this disease from root cause and therefore achieves good effects.
Prognosis of Purpura Nephritis
Prognosis of Purpura Nephritis is associated with many factors, including patient’s age, pathological type, severity and break out of skin purpura.
Usually, Purpura Nephritis in children has good prognosis; People with following pathological types have bad prognosis: sclerosis of glomerulus, fibrosis of renal interstitials and atrophy of renal tubules; prognosis is bad when a patient has frequent break out of skin purpura.
Saturday, 8 October 2011
Treating Polycystic Kidney Disease (PKD) with Immunotherapy
Polycystic Kidney Disease (PKD) is a hereditary disease. That is to say, patients with Polycystic Kidney Disease (PKD) have a family history of this disease. For most patients with PKD, they know this disease in their childhood and many of them have seen their relatives die of end-stage renal failure. In this case, they feel helpless in life. Is their any way to help them out?
When transfused into the body with impair kidney function,Immunotherapy can go to the lesions directly. There, they produce more Immunotherapy by self renewing and then these cells differentiate into renal intrinsic cells to replace the dead ones. Renal intrinsic cells refer to functional cells in nephrons, tiny filters which are in charge of kidney function. When dead intrinsic cells are replaced by new ones, kidney function is improved.
What’ more, Immunotherapy also offer assistance in stimulating damaged intrinsic cells to self repair.
When the dead renal intrinsic cells are replaced and the damaged ones are repaired, kidney function can be well rebuilt.
Is Immunotherapy suitable for anyone with PKD?
In fact,Immunotherapy is mostly suitable for patients with impaired kidney function. As is known to all, pressure from those big cysts surly causes damage to cells and tissues of the kidneys, resulting in impaired kidney function. And impaired kidney function is the real reason that PKD develops into end-stage renal failure. In western medicine, there is no medication that can treat impaired kidney function.
How does a person with PKD know whether he has impaired kidney function or not?
The way to know one’s kidney function is to test for the Glomerular Filtration Rate (GFR) or Creatinine Clearance. Normal GFR or Creatinine Clearance signifies an intact kidney function.
How to treat patients with PKD but without impaired kidney function?
For patients without impaired kidney function, cysts are their big trouble. Untreated or poorly treated, cysts will cause impaired kidney function in the future. Then how to treat those cysts? Apart from dietary treatment and antihypertensive medications used to slow down the progression of PKD, there exists a medicine which can stop and even shrink the cysts. This medicine is called Micro-Chinese Osmotherapy.
Micro-Chinese Medicine Osmotherapy, similar to Chinese herb medicine, is a natural therapy. Without surgery, it can deal with cysts in the kidneys. How dose it work then?
It works on enlarging blood vessels, speeding up blood circulation on cysts walls and restraining secretion of cyst fluid. In this case, small cysts will not grow bigger; and it also works on improving the permeability of the cysts wall. In this case, cyst fluid flows out of the cysts and thereby big cysts shrink. Meanwhile, pressure from cysts will be relieved, and the kidneys will not be further damaged. What’s more, some ingredients in Micro-Chinese medicine help to lower urea and hypertension, cure anemia and edema.
Conclusion
Although treating Polycystic Kidney Disease (PKD) with Immunotherapy is a relatively new way to help patients with PKD to get rid of sufferings from PKD, it has brought hope for their life. Till now, many clinical practices have shown Immunotherapy is effective in treating PKD. The writer hopes that more and more patients can be helped by this therapy in the future.
When transfused into the body with impair kidney function,Immunotherapy can go to the lesions directly. There, they produce more Immunotherapy by self renewing and then these cells differentiate into renal intrinsic cells to replace the dead ones. Renal intrinsic cells refer to functional cells in nephrons, tiny filters which are in charge of kidney function. When dead intrinsic cells are replaced by new ones, kidney function is improved.
What’ more, Immunotherapy also offer assistance in stimulating damaged intrinsic cells to self repair.
When the dead renal intrinsic cells are replaced and the damaged ones are repaired, kidney function can be well rebuilt.
Is Immunotherapy suitable for anyone with PKD?
In fact,Immunotherapy is mostly suitable for patients with impaired kidney function. As is known to all, pressure from those big cysts surly causes damage to cells and tissues of the kidneys, resulting in impaired kidney function. And impaired kidney function is the real reason that PKD develops into end-stage renal failure. In western medicine, there is no medication that can treat impaired kidney function.
How does a person with PKD know whether he has impaired kidney function or not?
The way to know one’s kidney function is to test for the Glomerular Filtration Rate (GFR) or Creatinine Clearance. Normal GFR or Creatinine Clearance signifies an intact kidney function.
How to treat patients with PKD but without impaired kidney function?
For patients without impaired kidney function, cysts are their big trouble. Untreated or poorly treated, cysts will cause impaired kidney function in the future. Then how to treat those cysts? Apart from dietary treatment and antihypertensive medications used to slow down the progression of PKD, there exists a medicine which can stop and even shrink the cysts. This medicine is called Micro-Chinese Osmotherapy.
Micro-Chinese Medicine Osmotherapy, similar to Chinese herb medicine, is a natural therapy. Without surgery, it can deal with cysts in the kidneys. How dose it work then?
It works on enlarging blood vessels, speeding up blood circulation on cysts walls and restraining secretion of cyst fluid. In this case, small cysts will not grow bigger; and it also works on improving the permeability of the cysts wall. In this case, cyst fluid flows out of the cysts and thereby big cysts shrink. Meanwhile, pressure from cysts will be relieved, and the kidneys will not be further damaged. What’s more, some ingredients in Micro-Chinese medicine help to lower urea and hypertension, cure anemia and edema.
Conclusion
Although treating Polycystic Kidney Disease (PKD) with Immunotherapy is a relatively new way to help patients with PKD to get rid of sufferings from PKD, it has brought hope for their life. Till now, many clinical practices have shown Immunotherapy is effective in treating PKD. The writer hopes that more and more patients can be helped by this therapy in the future.
How Do Hypertensive Nephropathy Patients Eat
How Do Hypertensive Nephropathy Patients Eat
Hypertensive Nephropathy patients not only need to receive standard and reasonable treatment, but also need to pay attention to diet principle. How do Hypertensive Nephropathy patients eat? Now we will explain it in detail.
1. Controlling calorie supply
The quantity of heat should depend on patients' condition. Because Hypertensive Nephropathy patients often have lipid metabolism disorders, reducing intake of fat can not only help to control heat but also improve metabolic disorders.
2. Low-salt and high-Vitamin Diet
Hypertensive Nephropathy patients should control intake of salt and should not eat salty food. Also they should eat less of food containing antiseptic. They should ensure plenty of vitamin intake, especially Vitamine B which can help regulate metabolism within body. If necessary, patients can take vitamin supplements.
3. Drinking tea properly
Tea polyphenols is important for fat metabolism of human body, which can clear away heat and toxic material and soften blood vessels.
4. Protein is essential nutrients for human body. But intake of too much protein will increase patients' kidney burden and the kidney damage will aggravate. Insufficient protein intake will affect the body's nutrition supply. So intake of protein should depend on kidney condition: If renal damage is not obvious, intake of protein should be about 50 gram each day. If serum creatinine, urea nitrogen occur, intake of protein should be reduced to 20-40 gram each day.
5. Restricting salt intake
Intake of salt should be reduced to less than 6 g/day gradually. Reducing salt intake properly will help lower blood pressure and reduce the body's sodium and water retention.
So Hypertensive Nephropathy patients should analyse their diet under the doctor's guidance first. Then they should change their bad eating habits and restrict some food, which can enhance the quality of their life.
Any other questions about diet of Hypertensive Nephropathy patients.
Hypertensive Nephropathy patients not only need to receive standard and reasonable treatment, but also need to pay attention to diet principle. How do Hypertensive Nephropathy patients eat? Now we will explain it in detail.
1. Controlling calorie supply
The quantity of heat should depend on patients' condition. Because Hypertensive Nephropathy patients often have lipid metabolism disorders, reducing intake of fat can not only help to control heat but also improve metabolic disorders.
2. Low-salt and high-Vitamin Diet
Hypertensive Nephropathy patients should control intake of salt and should not eat salty food. Also they should eat less of food containing antiseptic. They should ensure plenty of vitamin intake, especially Vitamine B which can help regulate metabolism within body. If necessary, patients can take vitamin supplements.
3. Drinking tea properly
Tea polyphenols is important for fat metabolism of human body, which can clear away heat and toxic material and soften blood vessels.
4. Protein is essential nutrients for human body. But intake of too much protein will increase patients' kidney burden and the kidney damage will aggravate. Insufficient protein intake will affect the body's nutrition supply. So intake of protein should depend on kidney condition: If renal damage is not obvious, intake of protein should be about 50 gram each day. If serum creatinine, urea nitrogen occur, intake of protein should be reduced to 20-40 gram each day.
5. Restricting salt intake
Intake of salt should be reduced to less than 6 g/day gradually. Reducing salt intake properly will help lower blood pressure and reduce the body's sodium and water retention.
So Hypertensive Nephropathy patients should analyse their diet under the doctor's guidance first. Then they should change their bad eating habits and restrict some food, which can enhance the quality of their life.
Any other questions about diet of Hypertensive Nephropathy patients.
Side Effects of Corticosteroids in Nephrotic Syndrome
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.
Many diabetic patient need it.
But Do you Know Side Effects of Corticosteroids in Nephrotic Syndrome?
Corticosteroids are frequently used in treating Nephrotic Syndrome. This treatment are often called hormonotherapy. Objectively speaking, hormonotherapy is effect in treating symptoms of Nephrotic Syndrome. However, there are many side effects of Corticosteroids, especially long-term receiving this therapy. The following passages nearly generalize all major side effects.
Infection
Corticosteroids can effectively suppress the immune system, so long-term use will decrease patients’ immunity. Under such condition, patients are easy to be infected by bacteria, tubercle bacillus, fungus, virus or others. When patients develop infection, their inflammatory reaction is usually atypical. Missed diagnosis often happens. Besides, infection is difficult to control and easy to diffuse. Among these infections, hematogenous dissemination tuberculosis and Gut infection caused by fungus are most severe. They may cause life-threatening danger.
High blood pressure and swelling
This is related with retention of water and sodium, caused by corticosteroids. When using corticosteroids, patients should be monitored closely. If needed, diuretics and medicine of lowering blood pressure should be given.
Ulcer
Corticosteroids can promote gastric acid and pepsase secreting. And therefore too much gastric acid and pepsase induce ulcer and even ulcer with hemorrhage and perforation. Hence, people with ulcer should be careful when using Corticosteroids.
Osteoporosis
Corticosteroids can restrain osteoblast activity, calcium absorption of intestines and osteosis, as well as promoting Bone absorption, resulting in Osteoporosis. Therefore, it is better to take Vitamin D and calcium tablet for patients receiving long-term hormonotherapy, especially the elderly patients.
Avascular Necrosis of the Femoral Head
Hormonotherapy, especially therapy with large amount of corticosteroids can cause obstruction of bone microcirculation, leading to Avascular Necrosis of the Femoral Head. If patients have uncomfortable feeling or pain, they are suggested to do Femoral head X-ray or Magnatic Resonance Imaging (MRI).
Electrolyte disturbance
Corticosteroids can promote excretion of potassium, resulting in hypokalemia.
Glycosuria
Corticosteroids can restrain insulin of using glucose and promote neoglycogenesis, leading to increase of glucose in blood and thereby causing Glycosuria.
Hyperlipidaemia
Long-term hormonotherapy causes Hyperlipidaemia, promoting atherosclerosis.
Poor Wound Healing
It is related with the fact that corticosteroids can restrain protein synthesis, promote proteolysis and restrain mechanocyte of its functions.
Mental state
Patients using corticosteroids may have abnormal mental state. Excessive excitability and insomnia may occur.
Physical shape
Fat face and body, limb muscle atrophy and wrinkled skin are the most common physical changes occurring among patients receiving hormonotherapy.
In conclusion, patients should be careful when receiving hormonotherapy. Don’t use corticosteroids randomly. Consult the doctor before taking action.
For you health,You can choose better method to treat diabetes.
Many diabetic patient need it.
But Do you Know Side Effects of Corticosteroids in Nephrotic Syndrome?
Corticosteroids are frequently used in treating Nephrotic Syndrome. This treatment are often called hormonotherapy. Objectively speaking, hormonotherapy is effect in treating symptoms of Nephrotic Syndrome. However, there are many side effects of Corticosteroids, especially long-term receiving this therapy. The following passages nearly generalize all major side effects.
Infection
Corticosteroids can effectively suppress the immune system, so long-term use will decrease patients’ immunity. Under such condition, patients are easy to be infected by bacteria, tubercle bacillus, fungus, virus or others. When patients develop infection, their inflammatory reaction is usually atypical. Missed diagnosis often happens. Besides, infection is difficult to control and easy to diffuse. Among these infections, hematogenous dissemination tuberculosis and Gut infection caused by fungus are most severe. They may cause life-threatening danger.
High blood pressure and swelling
This is related with retention of water and sodium, caused by corticosteroids. When using corticosteroids, patients should be monitored closely. If needed, diuretics and medicine of lowering blood pressure should be given.
Ulcer
Corticosteroids can promote gastric acid and pepsase secreting. And therefore too much gastric acid and pepsase induce ulcer and even ulcer with hemorrhage and perforation. Hence, people with ulcer should be careful when using Corticosteroids.
Osteoporosis
Corticosteroids can restrain osteoblast activity, calcium absorption of intestines and osteosis, as well as promoting Bone absorption, resulting in Osteoporosis. Therefore, it is better to take Vitamin D and calcium tablet for patients receiving long-term hormonotherapy, especially the elderly patients.
Avascular Necrosis of the Femoral Head
Hormonotherapy, especially therapy with large amount of corticosteroids can cause obstruction of bone microcirculation, leading to Avascular Necrosis of the Femoral Head. If patients have uncomfortable feeling or pain, they are suggested to do Femoral head X-ray or Magnatic Resonance Imaging (MRI).
Electrolyte disturbance
Corticosteroids can promote excretion of potassium, resulting in hypokalemia.
Glycosuria
Corticosteroids can restrain insulin of using glucose and promote neoglycogenesis, leading to increase of glucose in blood and thereby causing Glycosuria.
Hyperlipidaemia
Long-term hormonotherapy causes Hyperlipidaemia, promoting atherosclerosis.
Poor Wound Healing
It is related with the fact that corticosteroids can restrain protein synthesis, promote proteolysis and restrain mechanocyte of its functions.
Mental state
Patients using corticosteroids may have abnormal mental state. Excessive excitability and insomnia may occur.
Physical shape
Fat face and body, limb muscle atrophy and wrinkled skin are the most common physical changes occurring among patients receiving hormonotherapy.
In conclusion, patients should be careful when receiving hormonotherapy. Don’t use corticosteroids randomly. Consult the doctor before taking action.
For you health,You can choose better method to treat diabetes.
Wednesday, 5 October 2011
Neglectful Tips about Kidney Cyst
Neglectful Tips about Kidney Cyst?
When people are diagnosed as Kidney Cyst instead of Polycystic Kidney Disease, they will have a deep breath with relief for they think there would be nothing wrong with their kidneys. Compared with Polycystic Kidney Disease, Kidney cyst indeed usually causes no severe damages to kidneys as well as renal functions. However, as the epithelial cells of cysts own great power of growing, they might develop into cancerous cells under stimulation outside, such as unreasonable dietary regimen, although the risk is much less. What’s worse, it is possible for doctors to mistaken the cancerous cysts as benign kidney cysts. Thus there is something neglectful or tips people with Kidney Cyst should be pay a close attention to.
Quit smoking and alcohol
Smoking has nothing useful but damaging the health of human beings. Besides harming lung, Nicotine in tobacco will cause vasoconstriction and arteriosclerosis, reducing the amount of blood in viscera including kidney. Less blood and slow blood flow indirectly worsen the obstruction of renal tubules and promote the growth of cysts. Smoking people are usually troubled with unstable blood pressure, which is the main cause of severe symptoms of patients with Renal Cyst, such as vomiting and nausea.
Long standing alcoholism will elevate blood pressure and cause hydropenia in cells for alcohol is able to unite free water in those cells. What’s worse, alcohol can activate protein of cysts and increase the fluid in those cysts. Although commonly kidney cysts will not cause more creatinine in blood, alcohol can promote Rhabdomyolysis and elevate blood creatinine. In addition, people of alcoholism will show anemia, high blood lipid, frequent urination and other causes or symptoms of damaged renal functions.
Receiving the regular checkups
If you are just diagnosed with Renal Cyst, it would be better for you to continue the regular checkups. If the cysts are too small to distinguish the benign cysts from the cancerous cysts, the potential danger undermine your health. Moreover, the checkups must be thorough and adopted B ultrasound and CT. B ultrasound fails in making out the nature of the cysts. With CT, the benign Renal Cyst usually has one cavity with smooth wall as well as clear fluid inside. If the cysts show irregular shapes and the uneven wall with burrs, they are probably cancerous cysts. In order to prevent metastasizing, doctors tend to suggest the patients receive radical nephrectomy. Even if the cysts are not cancerous, the regular checkups can find the growth of the cysts, which is useful to consider adopting early treatments and avoid severe symptoms.
According to the perspective of Chinese medical science, any treatment is much more important in enhancing immunity than in treating diseases. Thus, Kidney Cyst should be closely watched, avoiding its deterioration or cancerization.
When people are diagnosed as Kidney Cyst instead of Polycystic Kidney Disease, they will have a deep breath with relief for they think there would be nothing wrong with their kidneys. Compared with Polycystic Kidney Disease, Kidney cyst indeed usually causes no severe damages to kidneys as well as renal functions. However, as the epithelial cells of cysts own great power of growing, they might develop into cancerous cells under stimulation outside, such as unreasonable dietary regimen, although the risk is much less. What’s worse, it is possible for doctors to mistaken the cancerous cysts as benign kidney cysts. Thus there is something neglectful or tips people with Kidney Cyst should be pay a close attention to.
Quit smoking and alcohol
Smoking has nothing useful but damaging the health of human beings. Besides harming lung, Nicotine in tobacco will cause vasoconstriction and arteriosclerosis, reducing the amount of blood in viscera including kidney. Less blood and slow blood flow indirectly worsen the obstruction of renal tubules and promote the growth of cysts. Smoking people are usually troubled with unstable blood pressure, which is the main cause of severe symptoms of patients with Renal Cyst, such as vomiting and nausea.
Long standing alcoholism will elevate blood pressure and cause hydropenia in cells for alcohol is able to unite free water in those cells. What’s worse, alcohol can activate protein of cysts and increase the fluid in those cysts. Although commonly kidney cysts will not cause more creatinine in blood, alcohol can promote Rhabdomyolysis and elevate blood creatinine. In addition, people of alcoholism will show anemia, high blood lipid, frequent urination and other causes or symptoms of damaged renal functions.
Receiving the regular checkups
If you are just diagnosed with Renal Cyst, it would be better for you to continue the regular checkups. If the cysts are too small to distinguish the benign cysts from the cancerous cysts, the potential danger undermine your health. Moreover, the checkups must be thorough and adopted B ultrasound and CT. B ultrasound fails in making out the nature of the cysts. With CT, the benign Renal Cyst usually has one cavity with smooth wall as well as clear fluid inside. If the cysts show irregular shapes and the uneven wall with burrs, they are probably cancerous cysts. In order to prevent metastasizing, doctors tend to suggest the patients receive radical nephrectomy. Even if the cysts are not cancerous, the regular checkups can find the growth of the cysts, which is useful to consider adopting early treatments and avoid severe symptoms.
According to the perspective of Chinese medical science, any treatment is much more important in enhancing immunity than in treating diseases. Thus, Kidney Cyst should be closely watched, avoiding its deterioration or cancerization.
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