What Cause Renal Failure

Renal Failure is a common kidney disease, It must be treated in time.Or kidney patient must dialysis for his kidney.so If you have Renal Failure,you must be treated in time.  But What Cause Renal Failure?  The causes are as following:  1. Hypovolemia: serious loss of blood volume may lead to Renal Failure.  2. Abnormal blood circulation:  Abnormal circulation may lead to obstruction of renal artery or vein, thus causing ischemia state, then aggravate injury on kidneys;  3. Drug abuse:  Due to kidneys are the main organ for eliminating toxins, most drugs will do harm to kidneys. For example, some patients with kidney disease take large amounts of diuretics which will cause the excessive loss of water, which may lead to Acute Renal Failure.  Comparing with Acute Renal Failure, causes of Chronic Renal Failure are complicated.  1. Common disease:  There are two kinds of disease may lead to Renal Failure. On one hand, kidney disease may develop into Renal Failure. Chronic glomerulonephritis is one of the common cause and including IgA Nephropathy, Mesangial Proliferative Glomerulonephritis and focal segmental sclerosing glomerulonephritis, etc. In addition, polycystic kidney disease,  reflux nephropathy, kidney stones and prostate disease can also cause Renal Failure.  On the other hand, other disease can also cause Renal Failure, such as poorly controlled diabetes, Hypertension and so on.  2. Infectious nephropathy:  Chronic Pyelonephritis, nephrotuberculosis, etc. Serious infection may lead to Renal Failure while patients with Renal Failure should also pay attention to avoiding infection.  3. Accumulation of ECM:  Eextracellular matrix (ECM) is not easily to be degraded, so the abundant deposition and of ECM will replace nephrons, thus leading continuous glomerulus sclerosis.  4. Gene factors:  Polycystic Kidney Disease and Alport syndrome are the main kidney disease relating with gene. Patients with family history of kidney disease should treat the disease timely to avoid Renal Failure.  5. Others:  ureteral obstruction,vasculitis, Multiple Myeloma and so on can also cause injury on kidneys, thus leading to the occurrence of Renal Failure.  Though Renal Failure is a serious stage of kidney disease, there still treatments for it. Seeing from the whole world, there are two main ways: kidney transplant and  Immunotherapy   Transplant. Kidney transplant is mature in technology, but it still have some disadvantages, such as long-term medicines for rejection, long-term waiting for suitable donor and so on.  Immunotherapy   is a new technology, so it can not be accept by most people, especially patients whose countries have no this technology. However, with the development of medical science, Immunotherapy   are applied by more and more people nowadays.